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But with ED, PDE5 might stop working cGMP way too swiftly and allow it to be more durable so that you can get or hold an erection. PDE5 inhibitors like sildenafil help decelerate PDE5 since it breaks down cGMP, which makes it easier to get tricky and remain challenging.A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Getting OTC medicine from ou